Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils

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Cytotoxic and apoptotic effects of root extract and tanshinones isolated from Perovskia abrotanoides Kar

Objective(s):Perovskia abrotanoides Kar., from family Lamiaceae, is a little known medicinal plant growing in various regions of Iran. In the present study, cryptotanshinone (CT), tanshinone 2A (Tan2A), and hydroxycryptotanshinone (HCT) were isolated and purified from the roots of P. abrotanoides. In addition, cytotoxic and apoptotic effects of total root extract (TE) and three purified tanshin...

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Potentiating effects of Perovskia abrotanoides Karel. on pentobarbital-induced sleep

OBJECTIVE Sleeplessness is the most common sleep disorder. In this study the hypnotic effect of the hydro-alcoholic extract (HAE) of Perovskia abrotanoides Karel. and its water fraction (WF), ethyl acetate fraction (EAF) and n-butanol fraction (NBF) were studied in mice. MATERIALS AND METHODS The test compounds were administered intraperitoneally to mice 30 min before the administration of so...

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Influence of Environment on Glandular Trichomes and Composition of Essential Oil of Perovskia abrotanoides Karel.

BACKGROUND Perovskia abrotanoides Karel. is a medicinal plant used in Iranian folk medicine as a pain killer. Forty-one components have been identified in P. abrotanoides samples collected from Baluchistan Province, and 29 components have been recognized in samples collected from Khorasan Province. The leaves of P. abrotanoides have glandular trichomes (capitates and peltate) on both sides of t...

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Ctotoxic and apoptogenic effects of Perovskia abrotanoides flower extract on MCF-7 and HeLa cell lines

OBJECTIVE Perovskia abrotanoides Karel, belongs to the family Lamiaceae and grows wild alongside the mountainous roads inarid and cold climate of Northern Iran. The anti-tumor activity of P. abrotanoides root extract has been shown previously. This study was designed to examine in vitro anti-proliferative and pro-apoptotic effects of flower extract of P. abrotanoides on MCF-7 and Hela cell line...

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The Antimicrobial Activity of Essential Oil from Perovskia abrotanoides Karel and its Main Components

In Iranian folk medicine, Perovskia abrotanoides is used for treatment of leishmaniasis. These patients may develop secondary infections with opportunistic microorganisms. Therefore, the antimicrobial activity of essential oil from aerial part of P. abrotanoides and its main components was evaluated against different microorganisms. Disc diffusion and broth micro dilution assays were used for i...

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ژورنال

عنوان ژورنال: Biological Research

سال: 2014

ISSN: 0717-6287

DOI: 10.1186/0717-6287-47-12